Virechana is the most popular and commonly employed panchakarma procedure where the patient is made to undergo controlled therapeutic purgation. It helps in detoxification of the body and gradually enhance the metabolic strength . It is the main treatment for diseases of pitta dosha predominance. It is highly beneficial in disorders of large intestine, gastrointestinal diseases, skin diseases, allergic conditions, neurological diseases, LBA, rheumatologic spectrum, autoimmune diseases etc